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Anticoagulant proteins and complications in pregnancy

Anticoagulant proteins and complications in pregnancy

Blood coagulation is determined by certain proteins in the body. Anticoagulation factors play an essential role in regulating how blood is coagulated. When they are found in low amounts in the body of a pregnant woman, they may increase the risk of serious pregnancy complications. Find out what role anticoagulant proteins play and what are the risks that arise when they are not within normal limits in pregnancy!

The role of anticoagulant proteins

If the blood clots too easily, blood clots may appear. In the situation in which it coagulates too slowly, there is the risk of internal bleeding. Anticoagulation factors - proteins S and Z - play a crucial role in the proper coagulation of blood.

Protein S, one of the most important anticoagulant factors, plays an essential role in preventing excessive blood clotting. It works in combination with another protein, called C. This complex protein contributes to the deactivation of other proteins, called Factor Va and Factor VIIIa, which favors the formation of blood clots.

Protein S maintains levels of these two proteins within normal limits and prevents coagulation problems.

Risks of low level of anticoagulant proteins in pregnancy

If the level of these proteins decreases, there is a risk of blood clots and very serious complications:

  • miscarriage;
  • preeclampsia;
  • insufficient development of the fetus;
  • bleeding;
  • premature birth;
  • the birth of a dead girl.

These complications arise from the fact that low levels of anticoagulant proteins contribute to the formation of clots in blood vessels that carry nutrients, oxygen and blood to the fetus. When the fetus is deprived of nutrients, serious problems arise in its development.

Early testing of anticoagulant protein levels in pregnancy is essential to prevent these complications, especially in pregnant women with hereditary coagulation disorders. And those with a medical history of miscarriage or previous pregnancy complications should be tested for levels of these anticoagulant factors.

The discovery provides important information to physicians about how pregnancy will evolve and the complications they may be subjected to. Testing the levels of anticoagulant proteins is most often done through a blood test.

However, there are other ways in which doctors can quickly detect the blood and problems that may result from it.

How is the level of anticoagulant proteins regulated in pregnancy?

If the presence of a low level of anticoagulant proteins in pregnancy is discovered, then the doctors will pass the pregnancy under strict supervision and administer anticoagulants, to prevent clots.

Among the most common anticoagulants given to pregnant women who have problems with the level of these proteins are heparin and warfarin. Even if it presents a slight risk of developing internal bleeding, doctors say that the formation of clots is much more dangerous for the fetus. In addition, careful supervision of pregnancy helps to effectively combat this risk.

Do you know of any cases where unbalanced levels of anticoagulant proteins in the body have caused pregnancy problems? Tell us your opinions in the comments section below!